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Utdanning

  • Can.med, Medisinsk fakultet, Universitetet i Oslo (1995)
  • Doktorgrad ved Medisinsk fakultet, Universitetet i Oslo (2001)

Stilling

  • Seniorforsker, Klinikk for revmatologi, poliklinikk og forskning, Diakonhjemmet sykehus
  • Overlege i revmatologi, Klinikk for revmatologi, poliklinikk og forskning, Diakonhjemmet sykehus

Interessefelt

  • Avansert medikamentell behandling av inflammatorisk revmatisk sykdom
  • Biomarkører
  • Legemiddelmonitorering
  • Biotilsvarende legemidler
  • Synoviale biopsier
  • Autoimmunitet
  • Vaksinerespons

E-post

Telefon

Besøksadresse

Diakonhjemmet sykehus
Diakonveien 12
0370 Oslo

Postadresse

Diakohjemmet sykehus
Postboks 23 Vinderen
0319 Oslo

Prosjekter

WP2 - Presisjonsmedisin

BIKE

Biopsier av synovitt i kneleddet fra pasienter med RA og OA

WP2 - Presisjonsmedisin

BioTest

Eksperimentell presisjonsmedisin

WP2 - Presisjonsmedisin

MDR-RA

Den norske studien for terapeutisk legemiddelovervåking

WP1 - Behandlingsstudier

NOR-SWITCH

Bytte fra originalpreparat til biotilsvarende legemiddel hos pasienter med inflammatorisk sykdom i ledd, tarm eller hud

WP2 - Presisjonsmedisin

Nor-vaC

Immunologisk respons på COVID-19 vaksine hos pasienter på immunosuppressiv behandling

WP1 - Behandlingsstudier

SQUEEZE

Maksimering av effekten av reseptbelagte legemidler ved revmatoid artritt 

WP2 - Presisjonsmedisin

START

Tidlig diagnose ved nylig oppstått leddbetennelse


Publikasjoner

Publikasjoner hentet fra Nasjonalt vitenarkiv (NVA):

Development of Machine Learning Models for Predicting Non-Remission in Early RA Highlights the Robust Predictive Importance of the RAID Score-Evidence from the ARCTIC Study

2025

Clinical consequences of infliximab immunogenicity and the effect of proactive therapeutic drug monitoring: exploratory analyses of the randomised, controlled NOR-DRUM trials

2024

Dynamics of SARS-CoV-2 immunity after vaccination and breakthrough infection in rituximab-treated rheumatoid arthritis patients: a prospective cohort study

2024

Incidence and outcome of COVID-19 following vaccine and hybrid immunity in patients on immunosuppressive therapy: identification of protective post-immunisation anti-RBD antibody levels in a prospective cohort study

2024

T cell responses to repeated SARS-CoV-2 vaccination and breakthrough infections in patients on TNF inhibitor treatment: a prospective cohort study

2024

Therapeutic serum level for adalimumab in rheumatoid arthritis: explorative analyses of data from a randomised phase III trial

2024

Humoral and cellular responses to a fifth bivalent SARS-CoV-2 vaccine dose in patients with immune-mediated inflammatory diseases on tumour necrosis factor inhibitors: a prospective cohort study

2024

Deficient SARS-CoV-2 hybrid immunity during inflammatory bowel disease

2024

Efficacy of a Tumor Necrosis Factor inhibitor in chronic low back pain with Modic changes type 1: The BackToBasic study A randomized controlled trial

2024

Adalimumab serum levels and anti-drug antibodies: associations to treatment response and drug survival in inflammatory joint diseases

2023

Improving patient access to biosimilar tumor necrosis factor inhibitors in immune-mediated inflammatory disease: lessons learned from Norway

2023

Hybrid and SARS-CoV-2-vaccine immunity in kidney transplant recipients

2023

Cytokine Patterns as Predictors of Antibiotic Treatment Effect in Chronic Low Back Pain with Modic Changes: Subgroup Analyses of a Randomized Trial (AIM Study)

2023

HLA-DQ2 is associated with anti-drug antibody formation to infliximab in patients with immune-mediated inflammatory diseases

2023

Longitudinal changes of serum cytokines in patients with chronic low back pain and Modic changes

2023

Humoral immune response to SARS-CoV-2 vaccination in patients with inflammatory bowel disease on immunosuppressive medication: association to serum drug levels and disease type

2023

EULAR points to consider for therapeutic drug monitoring of biopharmaceuticals in inflammatory rheumatic and musculoskeletal diseases

2022

Identification of SNPs associated with methotrexate treatment outcomes in patients with early rheumatoid arthritis

2022

Four SARS-CoV-2 vaccine doses or hybrid immunity in patients on immunosuppressive therapies: a Norwegian cohort study

2022

Immunogenicity and safety of a three-dose SARS-CoV-2 vaccination strategy in patients with immune-mediated inflammatory diseases on immunosuppressive therapy

2022

The persistence of anti-Spike antibodies following two SARS-CoV-2 vaccine doses in patients on immunosuppressive therapy compared to healthy controls—a prospective cohort study

2022

Assessing Immunogenicity of Biologic Drugs in Inflammatory Joint Diseases: Progress Towards Personalized Medicine

2022

Therapeutic drug monitoring in inflammatory bowel disease: implementation, utilization, and barriers in clinical practice in Scandinavia

2022

Risk factors for anti-drug antibody formation to infliximab: Secondary analyses of a randomised controlled trial

2022

Immunogenicity and Safety of Standard and Third-Dose SARS-CoV-2 Vaccination in Patients Receiving Immunosuppressive Therapy

2022

Humoral and cellular immune responses to two and three doses of SARS-CoV-2 vaccines in rituximab-treated patients with rheumatoid arthritis: a prospective, cohort study

2021

Serum etanercept concentrations in relation to disease activity and treatment response assessed by ultrasound, biomarkers and clinical disease activity scores: results from a prospective observational study of patients with rheumatoid arthritis.

2021

Effect of Therapeutic Drug Monitoring vs Standard Therapy During Maintenance Infliximab Therapy on Disease Control in Patients With Immune-Mediated Inflammatory Diseases: A Randomized Clinical Trial

2021

Immune complexes, innate immunity, and NETosis in ChAdOx1 vaccine-induced thrombocytopenia

2021

Serum golimumab concentration and anti-drug antibodies are associated with treatment response and drug survival in patients with inflammatory joint diseases: data from the NOR-DMARD study

2021

Macrophage migration inhibitory factor: A potential biomarker for chronic low back pain in patients with Modic changes

2021

Rheumatoid factor and falsely elevated results in commercial immunoassays: data from an early arthritis cohort

2021

Effect of Therapeutic Drug Monitoring vs Standard Therapy During Infliximab Induction on Disease Remission in Patients With Chronic Immune-Mediated Inflammatory Diseases: A Randomized Clinical Trial

2021

Therapeutic drug monitoring of infliximab compared to standard clinical treatment with infliximab: study protocol for a randomised, controlled, open, parallel-group, phase IV study (The NOR-DRUM study)

2020

The effect of infliximab in patients with chronic low back pain and Modic changes (the BackToBasic study): study protocol of a randomized, double blind, placebo-controlled, multicenter trial

2020

Efficacy and safety of CT-P13 in inflammatory bowel disease after switching from originator infliximab: Exploratory analyses from the NOR-SWITCH main and extension trials

2020

Associations between certolizumab pegol serum levels, anti-drug antibodies and treatment response in patients with inflammatory joint diseases: data from the NOR-DMARD study

2019

Long‐term efficacy and safety of biosimilar infliximab (CT‐P13) after switching from originator infliximab: Open‐label extension of the NOR‐SWITCH trial

2019

Biologiske legemidler innen revmatologi

2018

Confiance des rhumatologues quant au passage a un biosimilaire

2018

Reviewing the evidence for biosimilars: key insights, lessons learned and future horizons

2017

Switching from originator infliximab to biosimilar CT-P13 compared with maintained treatment with originator infliximab (NOR-SWITCH): a 52-week, randomised, double-blind, non-inferiority trial

2017

Interleukin-15 Induces Interleukin-17 Production by Synovial T Cell Lines from Patients with Rheumatoid Arthritis

2011

The ACPA isotype profile reflects long-term radiographic progression in rheumatoid arthritis

2010

Biomarkers in early rheumatoid arthritis: longitudinal associations with inflammation and joint destruction measured by magnetic resonance imaging and conventional radiographs

2010

Prediction of radiographic progression in rheumatoid arthritis and the role of antibodies against mutated citrullinated vimentin: results from a 10-year prospective study

2010